Conscious sedation reduces distress in children undergoing voiding cystourethrography and does not interfere with the diagnosis of vesicoureteric reflux: a randomized controlled study
2008
Anxiety in Children Undergoing VCUG: Sedation or No Sedation?
Sample size: 125
publication
Evidence: high
Author Information
Author(s): David W. Herd
Primary Institution: Starship Children's Hospital, University of Auckland
Hypothesis
Does sedation influence the ability to diagnose vesicoureteric reflux during VCUG?
Conclusion
Midazolam reduces distress during VCUG without interfering with voiding dynamics.
Supporting Evidence
- Midazolam was effective in reducing distress in children undergoing VCUG.
- 61% of the placebo group experienced serious or severe distress compared to 26% in the midazolam group.
- The number needed to treat to reduce serious or severe distress was 2.9.
Takeaway
This study found that giving children midazolam can help them feel less scared during a medical test called VCUG.
Methodology
Literature search and review of comparative studies including randomized controlled trials.
Limitations
The study was limited to children above the age of one year.
Participant Demographics
Children aged 1-14 years, with a mean age of 3.6 years.
Statistical Information
P-Value
2.9
Confidence Interval
95%CI 1.9–5.5
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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