Study protocol: The Intensive Care Outcome Network ('ICON') study
2008

The ICON Study: Long-Term Outcomes for ICU Survivors

Sample size: 1000 publication Evidence: high

Author Information

Author(s): Griffiths John A, Morgan Kayleigh, Barber Vicki S, Young J Duncan

Primary Institution: ICS Trials Group, Kadoorie Centre, John Radcliffe Hospital

Hypothesis

What are the long-term health-related quality of life and psychological outcomes for survivors of intensive care treatment?

Conclusion

The ICON study aims to provide comprehensive data on the long-term physical and psychological health of ICU survivors in the UK.

Supporting Evidence

  • The study will assess health-related quality of life using validated tools like the SF-36 and EQ-5D.
  • Anxiety and depression will be measured using the Hospital Anxiety and Depression Scale (HADS).
  • PTSD symptoms will be evaluated with the PTSD Civilian Checklist (PCL-C).
  • The study aims to recruit at least 1000 survivors per year, making it the largest prospective cohort study of its kind.

Takeaway

This study is like a big check-up for people who have been in intensive care, to see how they feel and live after they leave the hospital.

Methodology

A multi-centre, longitudinal study assessing health-related quality of life, anxiety, depression, and PTSD symptoms at 3, 6, and 12 months post-ICU discharge.

Potential Biases

There are many potential sources for bias due to the non-randomized nature of the study.

Limitations

The study may face challenges in participant recruitment and potential biases due to its non-randomized design.

Participant Demographics

Participants will be recruited from 20–30 ICUs in the UK, including adults who have experienced at least 24 hours of ICU care.

Digital Object Identifier (DOI)

10.1186/1472-6963-8-132

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