An effective strategy with tofacitinib for the management of focal myositis with rheumatoid arthritis: a case report
2024

Tofacitinib for Focal Myositis in Rheumatoid Arthritis: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Pan Jing, Zheng Haihong, Xu Juan, Pan Shaobiao

Primary Institution: Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University

Hypothesis

Can tofacitinib effectively manage focal myositis in a patient with rheumatoid arthritis?

Conclusion

Tofacitinib may be a valuable treatment option for managing focal myositis in patients with rheumatoid arthritis, especially when corticosteroid tapering is challenging.

Supporting Evidence

  • The patient was initially misdiagnosed with infections and did not respond to antibiotics.
  • Tofacitinib was introduced after corticosteroid tapering led to symptom recurrence.
  • The patient maintained a relapse-free status for over two years after treatment.

Takeaway

This study is about a woman with rheumatoid arthritis who had a rare muscle problem called focal myositis. She got better after taking a medicine called tofacitinib.

Methodology

The patient was treated with tofacitinib after being misdiagnosed and undergoing various treatments, with significant symptom improvement observed.

Potential Biases

Potential bias in diagnosis due to initial misdiagnoses and treatment responses.

Limitations

The case report is based on a single patient, limiting generalizability.

Participant Demographics

A 58-year-old female with a 10-year history of rheumatoid arthritis.

Digital Object Identifier (DOI)

10.3389/fimmu.2024.1502410

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication