Measuring Glycemic Impact of Low-Carbohydrate Foods
Author Information
Author(s): Wolever Thomas MS, Gibbs Alison L, Spolar Matt, Hitchner Elinor V, Heimowitz Colette
Primary Institution: Glycemic Index Laboratories, Inc.
Hypothesis
The study aims to evaluate the accuracy of equivalent-glycemic-load (EGL) as a measure of the glycemic impact of low-carbohydrate foods.
Conclusion
EGL is a valid measure of the glycemic impact of low-carbohydrate foods, accurate to within 1 g.
Supporting Evidence
- EGL values were determined for different doses of glucose and white bread.
- The accuracy of EGL was assessed by comparing estimated GL values with actual glucose consumed.
- The study showed that EGL is sensitive enough to detect a glycemic response equivalent to that produced by 3 g oral-glucose.
- Results indicated that EGL is valid across the range of 0–20 g CHO.
- Statistical analysis confirmed significant differences in glycemic responses across different carbohydrate doses.
Takeaway
This study shows a new way to measure how much low-carb foods affect blood sugar, and it works well for small amounts of carbs.
Methodology
The study involved randomized, cross-over trials with healthy subjects measuring blood glucose responses to various carbohydrate doses from white bread and glucose.
Potential Biases
Potential conflicts of interest due to affiliations with companies involved in low-carbohydrate diets.
Limitations
The study's findings may not apply to all populations, and the variability in individual responses to carbohydrate intake was significant.
Participant Demographics
48 subjects (15 male, 33 female; ages 19-71; BMI 18.5-36.5 kg/m2).
Statistical Information
P-Value
0.027
Confidence Interval
95% confidence-interval, ± 0.5 g
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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