Micronutrient Status in Patients with Severe Obesity Before and After Laparoscopic Sleeve Gastrectomy
Author Information
Author(s): Ciobârcă Daniela, Cătoi Adriana Florinela, Copăescu Cătălin, Iancu Mihaela, Pop Ioana Delia, Vodnar Dan Cristian, Cecan Andra Diana, Miere Doina, Filip Lorena, Crișan Gianina
Primary Institution: Iuliu Hatieganu University of Medicine and Pharmacy
Hypothesis
This study aims to investigate the changes in micronutrient levels at 6 and 12 months after LSG and the potential influence of sex or baseline BMI on these changes.
Conclusion
Overall, our findings revealed changes in micronutrient status across the follow-up period, except for vitamin B12.
Supporting Evidence
- Vitamin B12 and vitamin D did not change significantly.
- Iron, calcium, and parathormone levels differed significantly from baseline to 12 months after LSG.
- Ferritin significantly decreased from baseline to 6 months and 12 months after LSG.
- Sex or initial severe obesity exhibited significant modifying effects for 25(OH)D and calcium.
Takeaway
This study looked at how the vitamins and minerals in very overweight people changed after they had stomach surgery. It found that most nutrients changed over time, but vitamin B12 stayed the same.
Methodology
This observational longitudinal study analyzed the micronutrient levels of 50 patients with severe obesity before and at 6 and 12 months after laparoscopic sleeve gastrectomy.
Limitations
The study did not monitor patients' adherence to prescribed supplementation following LSG, which may affect the results.
Participant Demographics
The mean age of the patients was 46.5 years, with 68% females and 32% males.
Statistical Information
P-Value
p < 0.001 for iron, p = 0.01 for calcium, p < 0.001 for parathormone.
Confidence Interval
95% CI: 202 [163, 240] vs. 160 [130, 191] vs. 150 [115, 185]
Digital Object Identifier (DOI)
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