Prenatal Predictors and Early Postnatal Outcomes in Fetuses with Tricuspid Atresia
Author Information
Author(s): Kahramanoglu Ozge, Eyisoy Omer Gokhan, Demirci Oya
Primary Institution: Zeynep Kamil Women and Children’s Diseases Training and Research Hospital, Istanbul, Turkey
Hypothesis
To assess the prenatal course and early postnatal outcomes of fetuses diagnosed with tricuspid atresia and to identify predictors of survival.
Conclusion
Tricuspid atresia can be accurately diagnosed in utero, and factors like restrictive VSD and outflow tract obstructions are critical for early survival.
Supporting Evidence
- Among the 22 liveborn infants, survival at 12 months was 72%.
- Restrictive VSD and high ductus venosus pulsatility index were significantly associated with lower survival.
- Genetic testing identified a chromosomal anomaly in one case (trisomy 18).
- Pulmonary stenosis was observed in 13 fetuses, affecting survival rates.
Takeaway
This study looked at babies with a heart problem called tricuspid atresia and found that some heart issues can make it harder for them to survive after birth.
Methodology
This was a retrospective study analyzing medical records of fetuses diagnosed with tricuspid atresia, focusing on prenatal echocardiographic features and postnatal outcomes.
Potential Biases
Potential bias due to the retrospective design and exclusion of cases with incomplete records.
Limitations
The study's small sample size and retrospective nature limit the generalizability of the findings.
Participant Demographics
The median maternal age was 32 years, with 64% male and 36% female fetuses.
Statistical Information
P-Value
0.021
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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