Evaluation of acute kidney injury with pediatric-modified RIFLE criteria after pediatric cardiac surgery
2011

Acute Kidney Injury in Children After Heart Surgery

Sample size: 81 publication Evidence: moderate

Author Information

Author(s): Zeyneloglu P, Pirat A, Baskin E, Camkiran A, Araz C, Ozkan M, Bayraktar N, Arslan G

Primary Institution: Baskent University Hospital, Ankara, Turkey

Hypothesis

The study aims to evaluate children with acute kidney injury after pediatric cardiac surgery using pediatric-modified RIFLE criteria.

Conclusion

AKI develops in 26% of patients after pediatric cardiac surgery, with younger patients showing higher serum cystatin C levels and inotrope scores.

Supporting Evidence

  • Twenty-one children (26%) developed AKI.
  • Patients with AKI were significantly younger than those without AKI.
  • Postoperative 24-hour inotrope scores were significantly higher in children who developed AKI.
  • Serum cystatin C concentrations were significantly increased in AKI patients at 2 hours after CPB.

Takeaway

Some kids can get sick kidneys after heart surgery, and younger kids might have more problems.

Methodology

Eighty-one children undergoing cardiopulmonary bypass for surgical correction of acyanotic congenital heart disease were prospectively enrolled, and blood samples were collected to measure serum cystatin C and creatinine levels.

Participant Demographics

Children undergoing cardiac surgery for congenital heart disease.

Statistical Information

P-Value

P = 0.002

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/cc9520

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