Pathological complete response in advanced gastric stromal tumor after imatinib mesylate therapy: a case report
2011

Complete Response in Gastric Tumor After Imatinib Treatment

Sample size: 1 publication Evidence: low

Author Information

Author(s): El Mesbahi Omar, Brahmi Sami Aziz, Akasbi Yousra, El Mrabet Fatima Zahra, Touyar Anas, Ossaden Abdelmalek, Znati Kaoutar, Maazaz Khalid, Amarti Affaf, Tizniti Siham, Taleb Khalid Ait, Ibrahimi Adil

Primary Institution: Hassan II University Hospital, Fez, Morocco

Hypothesis

Can imatinib mesylate lead to a complete pathological response in advanced gastrointestinal stromal tumors?

Conclusion

The patient achieved a complete pathological response after treatment with imatinib mesylate.

Supporting Evidence

  • The patient had a pathological complete response after neoadjuvant treatment with imatinib mesylate.
  • Imatinib mesylate is the standard treatment for advanced gastrointestinal stromal tumors.
  • Complete response to imatinib is rare, making this case noteworthy.

Takeaway

A woman with a stomach tumor got better after taking a medicine called imatinib, which helped her body fight the tumor completely.

Methodology

The patient received six months of imatinib mesylate treatment followed by surgery.

Limitations

The molecular biology examination was not done, and the patient did not undergo FDG-PET due to its unavailability.

Participant Demographics

54-year-old Arab woman

Digital Object Identifier (DOI)

10.1186/1752-1947-5-197

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