GPCRdb in 2025: New Features and Data for Odorant Receptors
Author Information
Author(s): Herrera Luis P Taracena, Andreassen Søren N, Caroli Jimmy, Rodríguez-Espigares Ismael, Kermani Ali A, Keserű György M, Kooistra Albert J, Pándy-Szekeres Gáspár, Gloriam David E
Primary Institution: University of Copenhagen
Conclusion
The 2025 release of GPCRdb significantly enhances the database by adding all human odorant receptors and new tools for data visualization and ligand search.
Supporting Evidence
- The GPCR database GPCRdb now includes all 407 human odorant receptors and their orthologs.
- New tools allow users to visualize their own data on receptor plots.
- Structure models of physiological ligand complexes have been added to the database.
Takeaway
This study updates a database that helps scientists understand how certain receptors in our body work, especially those related to smell, and adds new tools to make it easier to use.
Methodology
The study involved updating the GPCRdb database with new data on human odorant receptors and implementing new tools for data mapping and ligand searches.
Digital Object Identifier (DOI)
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