Enriched Environment Experience Overcomes Learning Deficits and Depressive-Like Behavior Induced by Juvenile Stress
2009

Enriched Environment Experience Overcomes Learning Deficits and Depressive-Like Behavior Induced by Juvenile Stress

Sample size: 114 publication 10 minutes Evidence: high

Author Information

Author(s): Ilin Yana Richter-Levin, Gal Richter-Levin

Primary Institution: The Institute for the Study of Affective Neuroscience (ISAN), University of Haifa, Israel

Hypothesis

Does an enriched environment reverse the effects of juvenile stress on emotional and cognitive behavior in adulthood?

Conclusion

The study found that an enriched environment can reverse most of the negative effects of juvenile stress on behavior and brain function in rats.

Supporting Evidence

  • Juvenile stress led to anxiety- and depressive-like behaviors in adulthood.
  • Enriched environment reversed the effects of juvenile stress on behavior.
  • Stress affected body weight gain in the short term but not in the long term.
  • Rats in enriched environments showed better learning abilities compared to stressed rats.

Takeaway

Rats that experienced stress as kids acted sad and anxious as adults, but giving them a fun environment helped them feel better and learn better.

Methodology

The study involved exposing rats to juvenile stress and then placing them in an enriched environment to assess behavioral and physiological changes.

Limitations

The study was conducted on rats, which may not fully represent human conditions.

Participant Demographics

Male Sprague Dawley rats, aged 22 days at the start of the study.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0004329

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