The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
2006

Cissus quadrangularis for Weight Loss and Metabolic Syndrome

Sample size: 123 publication Evidence: moderate

Author Information

Author(s): Oben Julius, Kuate Dieudonne, Agbor Gabriel, Momo Claudia, Talla Xavio

Primary Institution: University of Yaoundé I, Cameroon

Hypothesis

The study investigates the efficacy of a Cissus quadrangularis formulation in managing metabolic syndrome, particularly weight loss and central obesity.

Conclusion

Cissus quadrangularis formulation appears to be useful in the management of weight loss and metabolic syndrome.

Supporting Evidence

  • Participants who received the formulation showed significant reductions in weight and central obesity.
  • Fasting blood glucose, total cholesterol, LDL-cholesterol, triglycerides, and C-reactive protein levels decreased significantly in the treatment groups.
  • The formulation was well-tolerated with fewer side effects compared to the placebo.

Takeaway

This study shows that a plant called Cissus quadrangularis can help people lose weight and improve health problems related to being overweight.

Methodology

The study was a randomized, double-blind, placebo-controlled trial involving 123 overweight and obese participants over 8 weeks.

Limitations

The study did not include an exercise regimen and relied solely on dietary control.

Participant Demographics

Participants were 47.2% male and 52.8% female, aged 19-50, with BMIs ranging from 25 to 45.6.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-511X-5-24

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