Inflammation and Stroke Risk in US Adults
Author Information
Author(s): Qiu Xichenhui, Huang Yiqing, Wei Changning, Wang Qun
Primary Institution: Shenzhen University, Shenzhen, Guangdong, China
Hypothesis
This study aimed to investigate the association between SII, SIRI, and stroke risk in US adults.
Conclusion
Elevated levels of SII and SIRI are associated with an increased risk of stroke in US adults.
Supporting Evidence
- The analysis revealed a significant positive association between stroke risk and both SII and SIRI after adjusting for confounding factors.
- Nonlinear relationships were described using smoothing curves and a two-tailed linear regression model.
Takeaway
If you have high levels of certain inflammation markers, you might be at a higher risk for having a stroke.
Methodology
A cross-sectional investigation utilized datasets from the National Health and Nutrition Examination Survey (NHANES) conducted between 2005 and 2018, using multivariate regression models.
Participant Demographics
Adults aged 20 to 85 years.
Statistical Information
P-Value
0.0016
Confidence Interval
95% CI = 0.98 to 1.65 for SII; 95% CI = 1.13 to 1.97 for SIRI
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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