Menopause and Colorectal Cancer
Author Information
Author(s): Franceschi S, Gallus S, Talamini R, Tavani A, Negri E, Vecchia C La
Primary Institution: Servizio di Epidemiologia, Centro di Riferimento Oncologico, Aviano, Italy
Hypothesis
Post-menopausal women who have never used hormone replacement therapy have a higher risk of colon cancer compared to premenopausal women.
Conclusion
Post-menopausal women without hormone replacement therapy are at a higher risk for colon cancer than their premenopausal counterparts.
Supporting Evidence
- Post-menopausal women who have never used hormone replacement therapy have a higher risk of colon cancer.
- The increased risk of colon cancer lasts about 10 years after menopause.
- This risk is particularly noted in lean women with lower oestradiol levels.
Takeaway
Women who have gone through menopause and haven't taken hormone therapy might get colon cancer more than women who are still menstruating.
Methodology
Case-control study comparing post-menopausal and premenopausal women.
Participant Demographics
Post-menopausal women who have never used hormone replacement therapy.
Digital Object Identifier (DOI)
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