Outdoor air pollution and emergency department visits for asthma among children and adults: A case-crossover study in northern Alberta, Canada
2007

Air Pollution and Asthma Emergency Visits in Edmonton

Sample size: 57912 publication 10 minutes Evidence: high

Author Information

Author(s): Paul J Villeneuve, Li Chen, Brian H Rowe, Frances Coates

Primary Institution: Health Canada

Hypothesis

Does outdoor air pollution increase emergency department visits for asthma among children and adults?

Conclusion

Exposure to ambient levels of air pollution is an important determinant of emergency department visits for asthma, especially among young children and the elderly.

Supporting Evidence

  • An increase in NO2 and CO levels was associated with a 50% and 48% increase in asthma ED visits among children aged 2-4 years.
  • Associations were strongest during the months of April to September.
  • Air pollution risk estimates remained largely unchanged after adjusting for aeroallergen levels.

Takeaway

Air pollution can make people with asthma feel worse, especially kids and older adults. When pollution levels go up, more people go to the hospital for asthma.

Methodology

A time-stratified case-crossover design was used to analyze 57,912 emergency department visits for asthma from 1992 to 2002, adjusting for temperature, humidity, and seasonal respiratory epidemics.

Potential Biases

Potential misclassification of asthma diagnoses and reliance on hospital data may introduce bias.

Limitations

The study relied on fixed-site monitoring for air pollution, which may not capture individual exposure accurately.

Participant Demographics

Participants included individuals aged 2 years and older, with a notable percentage being young children (12.5%) and elderly (8.1%).

Statistical Information

P-Value

<0.05

Confidence Interval

95% CI

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1476-069X-6-40

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