Transhiatal esophagectomy in a high volume institution
2008

Transhiatal Esophagectomy Outcomes

Sample size: 215 publication Evidence: moderate

Author Information

Author(s): Davies Andrew R, Forshaw Matthew J, Khan Aadil A, Noorani Alia S, Patel Vanash M, Strauss Dirk C, Mason Robert C

Primary Institution: St Thomas' hospital, Guy's and St Thomas', NHS foundation trust

Hypothesis

The study aims to assess the outcomes of transhiatal esophagectomy in a high-volume institution during a period of increased use of systemic oncological therapies.

Conclusion

Transhiatal esophagectomy is an effective approach for treating tumors of the infracarinal esophagus and esophagogastric junction, with low mortality and morbidity rates.

Supporting Evidence

  • The one-year survival rate was estimated at 81%.
  • The five-year survival rate was estimated at 48%.
  • Only 0.9% of patients experienced in-hospital deaths.
  • Major complications occurred in 30% of patients.

Takeaway

This study shows that a specific type of surgery for esophagus cancer is safe and helps many people live longer, especially when combined with chemotherapy.

Methodology

The study involved a retrospective analysis of 215 patients who underwent transhiatal esophagectomy, with data collected from consultant databases and cancer registry.

Potential Biases

Potential biases may arise from the single-institution setting and the retrospective nature of the data collection.

Limitations

The study is limited by its retrospective design and the lack of a control group for comparison.

Participant Demographics

The cohort consisted of 182 males and 33 females, with a median age of 65 years.

Statistical Information

P-Value

<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-7819-6-88

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