Effects of Gene–Lifestyle Interaction on Obesity Among Students
Author Information
Author(s): Egorova Emiliya S., Aseyan Kamilla K., Bikbova Elvina R., Zhilina Anastasia E., Valeeva Elena V., Ahmetov Ildus I.
Primary Institution: Kazan State Medical University
Hypothesis
This study aimed to examine the relationship between genetic and lifestyle factors and their interaction with obesity risk among university students.
Conclusion
Individuals with a higher genetic predisposition are more susceptible to becoming overweight or obese under certain lifestyle conditions.
Supporting Evidence
- The polygenic risk score explained 8.3% of the variance in BMI.
- Lifestyle factors accounted for 7.8% of the variance in BMI.
- The gene–lifestyle interaction model contributed 15% to BMI variance.
Takeaway
This study found that both genes and lifestyle choices can affect how likely students are to become overweight or obese.
Methodology
The study involved 658 university students who underwent anthropometric and genetic screening and completed lifestyle questionnaires.
Potential Biases
Self-reporting can lead to recall and social desirability bias.
Limitations
The study's cross-sectional design and reliance on self-reported data may introduce biases.
Participant Demographics
The sample included 531 females and 127 males, with a mean age of 21.6 years.
Statistical Information
P-Value
p<0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website