Takayasu arteritis in children
2008

Takayasu Arteritis in Children

Sample size: 4 publication Evidence: low

Author Information

Author(s): Al abrawi Safia, Fouillet-Desjonqueres Marine, David Louis, Barral Xavier, Cochat Pierre, Cimaz Rolando

Primary Institution: Département de pédiatrie, Hôpital Edouard-Herriot and Université Claude-Bernard Lyon, Lyon, France

Hypothesis

The aim of this report was to describe four children with Takayasu arteritis and summarize main published studies.

Conclusion

Takayasu arteritis is not rare in pediatric patients and can present with unexplained arterial hypertension.

Supporting Evidence

  • The mean age at presentation of the cases was 11 years.
  • Arterial hypertension was the most common mode of presentation.
  • Inflammation markers were always abnormal in the patients.
  • Treatment included prednisone, methotrexate, and mycophenolate mofetil.

Takeaway

Takayasu arteritis is a disease that affects blood vessels in children, causing high blood pressure and other symptoms. Early treatment is important to help kids feel better.

Methodology

The report describes four cases of pediatric Takayasu arteritis, detailing clinical presentations, treatments, and outcomes.

Limitations

The small sample size and retrospective nature of the report limit the ability to draw firm conclusions.

Participant Demographics

Three patients were Caucasian and one was Asian, with ages ranging from 8 to 15 years.

Digital Object Identifier (DOI)

10.1186/1546-0096-6-17

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