Factors associated with retention and adherence on Pre-Exposure Prophylaxis among men who have sex with men in Kigali, Rwanda
2024

Factors Affecting PrEP Retention and Adherence Among MSM in Kigali, Rwanda

Sample size: 439 publication 10 minutes Evidence: moderate

Author Information

Author(s): Mubezi Sezi, Malamba Samuel S., Rwibasira Gallican N., Uwineza Jeanne, Kayisinga Jean de Dieu, Remera Eric, Ikuzo Basile, Ndengo Emah, Umuhoza Nadege, Sangwayire Beata, Mwesigwa Richard C. N., Stamatakis Caroline E., Wandera Manasseh G., Oluoch Tom O., Kayirangwa Eugenie

Primary Institution: Society for Family Health (SFH), Kigali, Rwanda

Hypothesis

What factors are associated with retention and adherence to Pre-Exposure Prophylaxis (PrEP) among men who have sex with men (MSM) in Kigali, Rwanda?

Conclusion

The study found that MSM who were sex workers, lived in larger households, had more sexual partners, completed secondary education, and were circumcised were more likely to be retained on PrEP.

Supporting Evidence

  • 90% of MSM respondents were retained on PrEP at 3 months.
  • 73% of those retained reported good adherence to PrEP.
  • Sex workers had a significantly higher likelihood of being retained on PrEP.

Takeaway

This study looked at how well men who have sex with men stick to their HIV prevention medication in Rwanda, finding that those with more sexual partners and who are sex workers are more likely to keep taking it.

Methodology

A retrospective cross-sectional study using questionnaires to assess PrEP retention and adherence among MSM attending health facilities.

Potential Biases

Self-reported adherence could underestimate true adherence levels.

Limitations

The study's retrospective design limits the ability to establish cause-effect relationships, and self-reported data may introduce bias.

Participant Demographics

Participants were MSM aged 18 and above, with a majority employed and a significant portion identifying as sex workers.

Statistical Information

P-Value

0.004

Confidence Interval

95%CI: 1.569, 10.921

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pgph.0004063

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