Human Embryonic Stem Cells: Preclinical Perspectives
Author Information
Author(s): Deb Kaushik, Sarda Kanchan
Primary Institution: Manipal Institute of Regenerative Medicine
Conclusion
The review discusses the potential of human embryonic stem cells (hESCs) in therapies and the challenges that need to be addressed for their safe clinical application.
Supporting Evidence
- Human embryonic stem cells have potential for treating diseases.
- Challenges include ethical concerns and technical limitations in deriving and using hESCs.
- Immunogenicity and tumor formation are significant risks associated with hESC therapies.
Takeaway
Human embryonic stem cells can help treat diseases, but there are many challenges to make them safe for patients.
Methodology
The review summarizes various methods and challenges related to the derivation and application of hESCs in therapies.
Potential Biases
Potential biases may arise from the authors' perspectives on hESCs and their applications.
Limitations
The review does not provide specific experimental data or results, focusing instead on theoretical perspectives and challenges.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website