The Interplay of Uterine Health and Obesity: A Comprehensive Review
2024

The Interplay of Uterine Health and Obesity: A Comprehensive Review

publication Evidence: high

Author Information

Author(s): Šišljagić Dina, Blažetić Senka, Heffer Marija, Vranješ Delać Mihaela, Muller Andrijana

Primary Institution: University Hospital Center Osijek

Hypothesis

How does obesity affect uterine health and reproductive outcomes in women?

Conclusion

Obesity significantly disrupts uterine structure and function, leading to various reproductive health issues.

Supporting Evidence

  • Obesity leads to hormonal imbalances that can affect menstrual cycles and fertility.
  • Chronic inflammation associated with obesity can impair uterine function and increase the risk of pregnancy complications.
  • Insulin and leptin resistance in obesity can disrupt reproductive health outcomes.
  • Obesity is linked to an increased risk of endometrial cancer and other reproductive disorders.

Takeaway

Being overweight can make it harder for women to have babies because it can change how their uterus works.

Digital Object Identifier (DOI)

10.3390/biomedicines12122801

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