Phylogenetic distribution and predominant genotype of the avian infectious bronchitis virus in China during 2008-2009
2011

Study of Avian Infectious Bronchitis Virus in China (2008-2009)

Sample size: 80 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ji Jun, Xie Jingwei, Chen Feng, Shu Dingming, Zuo Kejing, Xue Chunyi, Qin Jianping, Li Hongmei, Bi Yingzuo, Ma Jingyun, Xie Qingmei

Primary Institution: South China Agricultural University

Hypothesis

What are the prevalent genotypes of avian infectious bronchitis virus (IBV) in China during 2008-2009?

Conclusion

The study found that nephropathogenic IBVs in China during 2008-2009 were mainly A2-like strains.

Supporting Evidence

  • 70 out of 80 strains caused serious kidney lesions in infected birds.
  • The strains were mostly isolated in winter and spring.
  • Phylogenetic analysis revealed that most recent field isolates belonged to A2-branch and HN08-branch.
  • Sequence analysis showed high variation among the isolated strains.

Takeaway

This study looked at sick chickens in China to see what types of a virus called IBV were making them sick, and found that most of the viruses were a specific type called A2.

Methodology

Eighty IBV isolates were identified using dwarf embryo tests and RT-PCR from various provinces in China.

Limitations

The study may not cover all IBV strains circulating in China, as it only includes isolates from specific provinces and time periods.

Participant Demographics

Isolates were taken from vaccinated chicken flocks across multiple provinces in China.

Digital Object Identifier (DOI)

10.1186/1743-422X-8-184

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