Heterochromatic threads connect oscillating chromosomes during prometaphase I in Drosophila Oocytes
2009
Heterochromatic Threads Connect Chromosomes in Drosophila Oocytes
publication
Evidence: moderate
Author Information
Author(s): Giovanni Bosco, Gregory P. Copenhaver
Primary Institution: University of Arizona
Hypothesis
How do achiasmate homologs manage to segregate properly during meiosis?
Conclusion
Achiasmate chromosomes can move together and are connected by heterochromatic DNA threads, which help ensure their proper segregation.
Supporting Evidence
- Achiasmate homologs can be found on the same side of the metaphase plate.
- Heterochromatic DNA threads connect achiasmate chromosomes.
- These threads may provide a chiasma-like function for proper segregation.
- Achiasmate chromosomes can participate in the dynamic movements characteristic of locked chromosomes.
Takeaway
In fruit flies, some chromosomes can stick together with special threads, helping them move correctly during cell division.
Methodology
The study visualized live Drosophila female meiotic chromosomes to observe achiasmate chromosome movement.
Limitations
The study raises more questions than it answers regarding the nature and function of the heterochromatic threads.
Digital Object Identifier (DOI)
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