Population travel increases the risk of Plasmodium falciparum infection in the highland population of Gardula Zone, South Ethiopia: a longitudinal study
2024

Travel Increases Malaria Risk in Highland Ethiopia

Sample size: 1672 publication 10 minutes Evidence: moderate

Author Information

Author(s): Assefa Muluken, Massebo Fekadu, Ashine Temesgen, Wegayehu Teklu

Primary Institution: Arba Minch University

Hypothesis

Does population travel increase the risk of Plasmodium falciparum infection in highland populations?

Conclusion

Traveling to lowland areas for agriculture significantly increases the risk of malaria infection among highland residents.

Supporting Evidence

  • 82 malaria cases were confirmed among 4,884 blood samples tested.
  • Travelers to lowland areas had a significantly higher risk of malaria infection.
  • Low bed net ownership and usage were reported among highland populations.

Takeaway

People living in highlands who travel to lowland areas for farming are more likely to get malaria.

Methodology

A longitudinal study was conducted with 1672 participants from 329 households, using blood samples and questionnaires to assess malaria incidence and risk factors.

Potential Biases

Potential recall bias in self-reported travel history and reliance on RDTs for malaria diagnosis.

Limitations

The study relied on RDTs for initial screening, which may miss low-density infections, and travel history was self-reported, potentially leading to recall bias.

Participant Demographics

Participants included 833 males and 839 females, with a mean age of 22.8 years; 62.8% were 15 years or older.

Statistical Information

P-Value

0.009

Confidence Interval

95% CI: 1.27–5.33

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0315900

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