Comparing Pain Relief in Kidney Stone Patients
Author Information
Author(s): Kheirollahi Abdol-Reza, Tehrani Mohammad, Bashashati Mohammad
Primary Institution: Lorestan University of Medical Sciences
Hypothesis
The combination of intranasal desmopressin and intramuscular hyoscine N-butyl bromide is more effective than hyoscine N-butyl bromide alone in treating acute renal colic.
Conclusion
The combination of hyoscine N-butyl bromide and desmopressin is more effective than hyoscine N-butyl bromide alone in patients with renal colic.
Supporting Evidence
- Patients in group B experienced a significant decrease in pain levels compared to group A after 60 minutes.
- No side effects were detected in this study.
- The study included 116 patients randomly divided into two groups.
Takeaway
This study found that using two medicines together helps people with kidney stone pain feel better faster than using just one medicine.
Methodology
This open-labeled clinical trial randomly assigned 116 patients with acute renal colic to receive either hyoscine N-butyl bromide alone or in combination with desmopressin, assessing pain levels using a visual analogue scale.
Limitations
The study did not explore the long-term effects of the treatments or the impact of different doses of desmopressin.
Participant Demographics
Patients aged 18 to 55 years with clinically diagnosed acute renal colic.
Statistical Information
P-Value
p = 0.001
Statistical Significance
p<0.05
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