Surgical Treatment of Children with Epidermolysis Bullosa
Author Information
Author(s): Karaman Ilić Maja, Kern Josipa, Babić Irena, Šimić Diana, Kljenak Antun, Majerić Kogler Višnja
Primary Institution: Children's Hospital of Zagreb
Hypothesis
Does the procedural consolidation concept (PCC) reduce the number of anesthesia sessions needed for treating children with epidermolysis bullosa (EB)?
Conclusion
PCC should be considered an option in the surgical treatment of children with EB.
Supporting Evidence
- After introducing PCC, the median number of surgical procedures per session increased from 2 to 4.
- The median number of complications per anesthesia session increased from 2 to 3 after PCC was introduced.
- The number of hospitalization days per surgical procedure was significantly lower after PCC.
Takeaway
The study found that a new way of doing surgery for kids with a skin condition called EB can help them have fewer anesthesia sessions, which is better for them.
Methodology
Retrospective analysis of medical records of children treated at Children's Hospital of Zagreb between April 1999 and December 2007.
Potential Biases
Potential biases due to the retrospective nature of the study and lack of data on patient age and co-morbidities.
Limitations
The study design was retrospective and did not include long-term follow-up data.
Participant Demographics
The sample consisted of 53 children with EB, including 31 males and 22 females, aged 1 to 23 years.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website