Anti-Obesity Effects of Seaweed-Derived Sulphated Polysaccharides
Author Information
Author(s): Magwaza S’thandiwe Nozibusiso, Chabalala Vunene Nkateko, Hlongwane Nothando Philile, Ismail Huda, Islam Md. Shahidul, Diederich Marc
Primary Institution: University of KwaZulu-Natal (Westville Campus), Durban, South Africa
Hypothesis
Can seaweed-derived sulphated polysaccharides mitigate obesity in animal models?
Conclusion
Seaweed-derived sulphated polysaccharides can reduce obesity-related parameters in animal models, but further research in humans is needed.
Supporting Evidence
- Seaweed-derived sulphated polysaccharides significantly reduced body weight gain in treated animals.
- SPs led to a decrease in epididymal fat size and adipocyte size.
- Treatment with SPs resulted in lower serum insulin and TNF-α levels.
- SPs improved lipid profiles by reducing total cholesterol and LDL-c levels.
Takeaway
Seaweed can help make you less fat by reducing how much you eat and how much fat your body stores.
Methodology
Systematic review and meta-analysis of animal model studies on the effects of seaweed-derived sulphated polysaccharides on obesity.
Potential Biases
Potential language bias due to inclusion of only English language studies.
Limitations
The study is limited to preclinical studies and may not represent all types of sulphated polysaccharides.
Participant Demographics
Animal models primarily included rats and mice.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI = −2.55, 2.83
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website