SLEEP: A GEROSCIENCE TARGET
2024
The Importance of Sleep in Aging
publication
Evidence: moderate
Author Information
Author(s): Judith Carroll
Primary Institution: University of California, Los Angeles
Hypothesis
Sleep is important for physiological restoration throughout the body and may influence biological aging.
Conclusion
Improving sleep may slow the aging process and enhance biological restoration.
Supporting Evidence
- Insomnia is related to biomarkers of aging including shortened telomere length and older epigenetic age.
- Experimentally restricting sleep in older adults led to increased DNA damage response.
- Treating insomnia in older adults resulted in lower transcripts for cellular senescence.
Takeaway
Getting good sleep helps our bodies heal and stay healthy as we get older, while not sleeping well can make us age faster.
Methodology
The study examined the effects of sleep on biological aging through biomarkers and gene expression changes.
Limitations
Many unknowns still exist regarding the mechanisms of how sleep affects biological aging.
Participant Demographics
Older adults were studied regarding their sleep patterns and biological aging.
Digital Object Identifier (DOI)
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