MS4A Superfamily Molecules in Tumors, Alzheimer’s, and Autoimmune Diseases
Author Information
Author(s): Luo Xuejiao, Luo Bin, Fei Lei, Zhang Qinggao, Liang Xinyu, Chen Yongwen, Zhou Xueqin
Primary Institution: The Army Medical University
Hypothesis
The MS4A superfamily plays critical roles in the pathogenesis of various diseases, including cancer, Alzheimer's disease, and autoimmune diseases.
Conclusion
In-depth research into MS4A superfamily members may clarify their ability to act as candidate biomarkers and therapeutic targets for these diseases.
Supporting Evidence
- MS4A proteins are selectively expressed on various immune cells.
- Some MS4A proteins function as chaperones that interact with immune receptors.
- Evidence suggests that MS4A proteins play critical roles in cancer, infections, allergies, and neurodegenerative diseases.
Takeaway
MS4A proteins help our immune system and are important in diseases like cancer and Alzheimer's. Understanding them better could help us find new treatments.
Methodology
The review summarizes recent progress in understanding the role of MS4A superfamily in various diseases, focusing on their molecular mechanisms.
Digital Object Identifier (DOI)
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