High-Level Ciprofloxacin Resistance in Neisseria gonorrhoeae: First Report from Israel
2001
High-Level Ciprofloxacin Resistance in Neisseria gonorrhoeae: First Report from Israel
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Michael Dan, Francesca Poch, Daniel Shpitz, Bracha Sheinberg
Primary Institution: Infectious Disease Unit, E. Wolfson Hospital, Holon, Israel
Hypothesis
Is ciprofloxacin effective in treating Neisseria gonorrhoeae infections?
Conclusion
The case highlights a significant resistance to ciprofloxacin in Neisseria gonorrhoeae, necessitating alternative treatments.
Supporting Evidence
- The isolate was found to be highly resistant with an MIC of 32 g/mL for ciprofloxacin.
- The patient experienced treatment failure with ciprofloxacin but improved with ceftriaxone.
- Gonorrhea incidence has been increasing in Israel, prompting a surveillance program.
Takeaway
One man had a gonorrhea infection that didn't get better with a common antibiotic, showing that some germs can become very strong against medicines.
Methodology
The isolate was tested for antibiotic susceptibility using the E-test method.
Limitations
The study is based on a single case report.
Participant Demographics
A 30-year-old male with no recent travel history outside Israel.
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