Insulin Resistance: Fasting vs Non-Fasting Blood Tests
Author Information
Author(s): Hancox Robert J, Landhuis C Erik
Primary Institution: University of Otago
Hypothesis
Fasting and non-fasting metabolic indices would be highly correlated.
Conclusion
Non-fasting measures of leptin, adiponectin, and their ratios correlate closely with fasting values and may be sufficient for population-based research.
Supporting Evidence
- Non-fasting levels of leptin and adiponectin were highly correlated with fasting values.
- Moderate correlations were found between fasting and non-fasting estimates of insulin sensitivity.
- The study suggests that non-fasting blood tests could simplify participation in epidemiological studies.
Takeaway
This study shows that you can check insulin levels without needing to fast overnight, making it easier for people to participate in studies.
Methodology
Participants provided fasting and non-fasting blood samples, and various metabolic indicators were measured and compared.
Potential Biases
Some participants may not have accurately reported their food intake before tests, introducing variability.
Limitations
The study did not compare non-fasting measures with the gold-standard euglycaemic clamp technique.
Participant Demographics
30 volunteers aged 28 to 48 years, 15 male and 15 female.
Statistical Information
P-Value
< 0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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