Metabolic Syndrome in Thai Schizophrenic Patients: A One-Year Follow-Up Study
Author Information
Author(s): Srisurapanont Manit, Likhitsathian Surinporn, Boonyanaruthee Vudhichai, Charnsilp Chawanun, Jarusuraisin Ngamwong
Primary Institution: Department of Psychiatry, Faculty of Medicine, Chiang Mai University
Hypothesis
This study aimed to assess the progress of metabolic abnormalities in Thai individuals with schizophrenia by estimating their one-year incidence rate of metabolic syndrome.
Conclusion
Thai schizophrenic patients are likely to develop metabolic syndrome, with their metabolic abnormalities potentially progressing rapidly within a year.
Supporting Evidence
- 20.0% of subjects developed metabolic syndrome within a year.
- All subjects who developed metabolic syndrome had 2 components at baseline.
- Metabolic abnormalities were very common in the studied population.
Takeaway
This study found that some people with schizophrenia in Thailand can develop health problems related to metabolism, like diabetes, within a year.
Methodology
Schizophrenic patients were screened, and those without metabolic syndrome at baseline were followed up at 6 and 12 months to assess the development of metabolic syndrome.
Potential Biases
Selection bias was minimized by including all patients who visited the clinic, but the switching of antipsychotic medications may have influenced the results.
Limitations
The study had a high dropout rate, a small sample size, and excluded patients with metabolic syndrome at baseline.
Participant Demographics
57 participants (24 males and 33 females) with a mean age of 37.5 years.
Statistical Information
P-Value
0.68
Confidence Interval
95% CI, 1.17–1.56
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website