Relapse of Neuromyelitis Optica After Lidocaine Treatment
Author Information
Author(s): Uzawa Akiyuki, Mori Masahiro, Masuda Saeko, Aoe Kazuhiko, Kuwabara Satoshi
Primary Institution: Chiba University
Hypothesis
Can intravenous lidocaine administration induce a relapse of neuromyelitis optica spectrum disorder?
Conclusion
The patient's optic neuritis was likely a relapse of neuromyelitis optica triggered by lidocaine administration.
Supporting Evidence
- The patient had a positive anti-aquaporin-4 antibody titre.
- Visual loss occurred the day after lidocaine treatment.
- Brain MRI revealed a new optic nerve lesion.
Takeaway
A woman with a nerve condition got worse after receiving a pain treatment called lidocaine, suggesting it might have caused her symptoms to return.
Methodology
Case report detailing the patient's medical history, treatment with intravenous lidocaine, and subsequent symptoms.
Potential Biases
Potential bias in interpreting the relationship between lidocaine and symptom relapse due to the case study design.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
59-year-old Japanese woman.
Digital Object Identifier (DOI)
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