N′-[(E)-2-Methoxybenzylidene]pyrazine-2-carbohydrazide
2011
Crystal Structure of a Pyrazine-Carbonyl-Hydrazone Compound
publication
Evidence: moderate
Author Information
Author(s): de Souza Marcus V. N., da Silva Lima Camilo H., Wardell James L., Wardell Solange M. S. V., Tiekink Edward R. T.
Primary Institution: Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos – Farmanguinhos
Conclusion
The study presents the crystal structure of N′-[(E)-2-Methoxybenzylidene]pyrazine-2-carbohydrazide, revealing its unique molecular arrangement and interactions.
Supporting Evidence
- All non-hydrogen atoms lie on a crystallographic mirror plane.
- An intramolecular hydrogen bond generates a stable ring structure.
- Molecules assemble into a two-dimensional array through specific contacts.
- Weak π–π interactions stabilize the stacking of layers in the crystal.
Takeaway
Scientists studied a new chemical compound and found out how its molecules are arranged and connected to each other.
Methodology
The compound was synthesized from 2-pyrazinehydrazide and 2-methoxybenzaldehyde, and its structure was analyzed using X-ray crystallography.
Digital Object Identifier (DOI)
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