VA-ECMO Assisted Thrombectomy for High-Risk Pulmonary Embolism
Author Information
Author(s): Zhou Zhenhang, Zhong Yaoyang, Hu Jianbo, Wu Zhonghua, Zou Liping, Deng Zhihe, Bi Guoshan, Shen Xin, Dai Xianpeng, Huang Zhijia, Xiong Guozuo, Xu Yiming, Deng Liming
Primary Institution: The Second Affiliated Hospital, Hengyang Medical School, University of South China
Hypothesis
The study aims to investigate the efficacy of VA-ECMO assisted percutaneous mechanical thrombectomy in patients with acute high-risk pulmonary embolism.
Conclusion
VA-ECMO-assisted PMT technology can rapidly improve pulmonary hemodynamics while maintaining stable blood flow, thereby reducing in-hospital mortality in high-risk patients with pulmonary embolism complicated by cardiac arrest.
Supporting Evidence
- All patients received percutaneous thrombectomy, achieving a 100% technical success rate.
- The mortality rate was 27.3% during the 90-day follow-up.
- The 12-month mortality rate was 36.4%.
- Patients showed significant improvement in pulmonary hemodynamics post-treatment.
Takeaway
Doctors used a special machine to help patients with serious lung clots, and it worked really well to save lives.
Methodology
This multicenter retrospective study included patients with acute high-risk PE treated with VA-ECMO-assisted PMT from January 2021 to June 2024, focusing on right/left ventricle ratio, biomarkers, and pulmonary artery pressure before and after treatment.
Potential Biases
Selection bias due to focusing on high-risk PE patients who underwent CPR.
Limitations
The study's limitations include its retrospective nature, small sample size, and non-randomized design.
Participant Demographics
The median age of participants was 54 years, with 6 males and 5 females.
Statistical Information
P-Value
0.0001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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