The Antimicrobial Effect of Silver Ion Impregnation into Endodontic Sealer against Streptococcus mutans
Author Information
Author(s): Kreth J., Kim D., Nguyen M., Hsiao G., Mito R., Kang M.K., Chugal N., Shi W.
Primary Institution: UCLA School of Dentistry
Hypothesis
The study aims to test the antimicrobial efficacy of silver ions against the oral bacterium S. mutans when incorporated into a root canal sealer.
Conclusion
The addition of silver ions enhances the antimicrobial activity of the Kerr root canal sealer against S. mutans.
Supporting Evidence
- Silver ions showed significant antimicrobial effects at concentrations of 5 and 10 mg/ml.
- Kerr sealer discs with 20% silver ions had the greatest zone of inhibition.
- Statistically significant differences were observed in the antimicrobial efficacy of silver ions when incorporated into the sealer.
Takeaway
This study found that adding silver to a dental sealer can help kill bad bacteria that cause tooth infections.
Methodology
The study used growth inhibition studies, bacterial viability tests, and confocal laser scanning microscopy to evaluate the antimicrobial efficacy of silver ions.
Limitations
The study is not comprehensive and cannot serve as the basis to recommend clinical application without further research.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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