Ketamine for Pain Relief in Complex Regional Pain Syndrome
Author Information
Author(s): Sunder Rani A, Toshniwal Gokul, Dureja GP
Primary Institution: All India Institute of Medical Sciences, New Delhi, India
Hypothesis
Can Ketamine be used as an adjuvant in sympathetic blocks to manage central sensitization following peripheral nerve injury?
Conclusion
Ketamine can provide significant relief for patients with debilitating heat allodynia and cognitive symptoms when used as an adjuvant in sympathetic blocks.
Supporting Evidence
- All three patients had severe pain and allodynia that did not respond to conventional treatments.
- Patients experienced significant pain relief after the addition of Ketamine to their treatment regimen.
- Ketamine was well tolerated with minimal side effects reported.
Takeaway
This study shows that Ketamine can help people with severe pain after an injury, especially when other treatments don't work.
Methodology
Case series of three patients with CRPS Type II treated with sympathetic blocks and Ketamine.
Potential Biases
Potential bias due to the subjective nature of pain assessment.
Limitations
Small sample size and lack of control group.
Participant Demographics
Three male patients aged 28 to 45 with gunshot wounds leading to CRPS Type II.
Digital Object Identifier (DOI)
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