Tobacco and Acute Leukaemia Risk in Adults
Author Information
Author(s): Kane E V, Roman E, Cartwright R, Parker J, Morgan G
Primary Institution: Leukaemia Research Fund Centre for Clinical Epidemiology at the University of Leeds
Hypothesis
Does smoking increase the risk of acute leukaemia in adults?
Conclusion
Smoking is associated with a higher risk of developing acute leukaemia, especially among current smokers.
Supporting Evidence
- Individuals who had smoked regularly were more likely to develop acute leukaemia than non-smokers.
- The association was strongest for current smokers.
- Risk estimates were raised in all groups except those who had smoked for fewer than 10 years.
- The odds ratio decreased for those who had stopped smoking for more than 10 years.
Takeaway
People who smoke are more likely to get a type of blood cancer called acute leukaemia than those who don't smoke.
Methodology
Self-reported smoking histories were collected during face-to-face interviews with patients and matched controls.
Limitations
No significant linear trends were found with years smoked or years stopped smoking.
Participant Demographics
807 patients with acute leukaemia and 1593 age- and sex-matched controls.
Statistical Information
Confidence Interval
95% CI 1.0–1.4
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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