Patient survival after D 1 and D 2 resections for gastric cancer
Author Information
Author(s): Cuschieri A, Weeden S, Fielding J, Bancewicz J, Craven J, Joypaul V, Sydes M, Fayers P
Primary Institution: University Department of Surgery, Ninewells Hospital and Medical School, Dundee, UK
Hypothesis
Does D 2 resection provide better long-term survival compared to D 1 resection for gastric cancer?
Conclusion
The study found no significant survival advantage for D 2 resection over D 1 resection in gastric cancer patients.
Supporting Evidence
- The 5-year survival rates were 35% for D 1 resection and 33% for D 2 resection.
- There was no difference in overall 5-year survival between the two surgical approaches.
- Clinical stages II and III, old age, and male sex were associated with poorer survival.
Takeaway
Doctors compared two types of surgery for stomach cancer and found that one type didn't help patients live longer than the other.
Methodology
Patients with gastric adenocarcinoma were randomized to receive either D 1 or D 2 resection, with follow-up for survival.
Limitations
The study may not account for all variables affecting survival, and the results may not apply to all patient populations.
Participant Demographics
Patients with histologically proven gastric adenocarcinoma, including a mix of clinical stages and ages.
Statistical Information
Confidence Interval
95% CI = –12%–8%
Digital Object Identifier (DOI)
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