A randomised controlled trial of nurse-managed trial conclusion following early phase cancer trial participation
2005

Nurse-Managed Support for Cancer Trial Participants

Sample size: 117 publication Evidence: moderate

Author Information

Author(s): K. Cox, E. Wilson, A. Arthur, R. Elkan, S. Armstrong

Primary Institution: University of Nottingham

Hypothesis

Does a nurse-managed intervention improve psychosocial outcomes for patients at the conclusion of early phase cancer trials?

Conclusion

The nurse-managed trial conclusion led to positive outcomes for patients who had recently completed a clinical trial.

Supporting Evidence

  • Patients in the intervention group felt more informed about the trial and their follow-up care.
  • Patient satisfaction with the intervention was high, with a median score of 4.5 out of 5.
  • There was no significant difference in anxiety and depression scores between the intervention and control groups.

Takeaway

This study shows that having a nurse help patients after they finish a cancer trial can make them feel better and more informed.

Methodology

A randomised controlled trial comparing nurse-managed follow-up with standard care for cancer trial participants.

Potential Biases

Patients may have provided different responses based on whether they completed questionnaires alone or with assistance.

Limitations

High attrition rate due to patient mortality and potential bias in questionnaire completion methods.

Participant Demographics

The average age was just under 60 years, with more men than women, and the majority were married.

Statistical Information

P-Value

P=0.27

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1038/sj.bjc.6602675

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