Lymphocytic Thyroiditis: Is Cytological Grading Important?
Author Information
Author(s): Alka Bhatia, Arvind Rajwanshi, Radharaman J Dash, Bhagwant R Mittal, Akshay K Saxena
Primary Institution: Postgraduate Institute of Medical Education and Research, Chandigarh, India
Hypothesis
Does cytological grading of lymphocytic thyroiditis correlate with clinical, biochemical, ultrasonographic, and radionuclide parameters?
Conclusion
Fine needle aspiration cytology remains the gold standard for diagnosing lymphocytic thyroiditis, but its grades do not correlate with other diagnostic parameters.
Supporting Evidence
- Most patients were females with a mean age of 34.2 years.
- Cytomorphology was diagnostic of lymphocytic thyroiditis in 98.68% of patients.
- No correlation was observed between cytological grades and other clinical parameters.
Takeaway
This study looked at patients with thyroiditis and found that the way we grade the disease under a microscope doesn't really match up with other tests we do.
Methodology
This was a prospective study involving 76 patients who underwent fine needle aspiration cytology and various clinical and biochemical assessments.
Potential Biases
Potential bias due to the selection of patients from a tertiary care clinic.
Limitations
The study had a small sample size and the statistical correlation was not significant for many parameters.
Participant Demographics
70 females (92.11%) and 6 males (7.89%), aged 6 to 60 years.
Statistical Information
P-Value
p>0.1
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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