Fulminant hemophagocytic lymphohistiocytosis induced by pandemic A (H1N1) influenza: a case report
2011
Severe Hemophagocytic Lymphohistiocytosis from H1N1 Influenza: A Case Report
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Willekens Christophe, Cornelius Aurélie, Guerry Mary-Jane, Wacrenier Agnès, Fourrier François
Primary Institution: Hôpital Roger Salengro, CHRU, Lille, France
Hypothesis
Can H1N1 influenza induce severe hemophagocytic lymphohistiocytosis?
Conclusion
H1N1 influenza can lead to severe hemophagocytic lymphohistiocytosis and multi-organ failure.
Supporting Evidence
- The patient developed severe hemophagocytic lymphohistiocytosis shortly after H1N1 influenza.
- Initial symptoms included unusual acute abdominal involvement.
- Histology showed significant apoptosis and increased cellular regeneration.
Takeaway
A woman got very sick from the flu and her body started attacking itself, which made her very ill and she sadly passed away.
Methodology
Case report detailing clinical presentation, laboratory findings, and histological examination.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
42-year-old Caucasian woman.
Digital Object Identifier (DOI)
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