Prevalence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in England
Author Information
Author(s): Luis Nacul, Eliana M. Lacerda, Derek Pheby, Peter Campion, Mariam Molokhia, Shagufta Fayyaz, Jose C. D. Leite, Fiona Poland, Amanda Howe, Maria L. Drachler
Primary Institution: London School of Hygiene and Tropical Medicine
Hypothesis
What is the prevalence and incidence of ME/CFS in three regions of England?
Conclusion
ME/CFS is not uncommon in England and represents a significant burden to patients and society.
Supporting Evidence
- The estimated minimum prevalence rate of ME/CFS was 0.2%.
- The overall estimated minimal yearly incidence was 0.015%.
- Prevalence rates varied by region, with London having the highest rates.
- Most cases conformed to the CDC-1994 definition.
Takeaway
This study found that many people in England suffer from a condition called ME/CFS, which makes them very tired and affects their daily lives.
Methodology
The study involved two cross-sectional surveys of 143,000 individuals aged 18 to 64 years from 29 general practices in three regions, using electronic searches and GP questioning to identify cases.
Potential Biases
Potential under-diagnosis of ME/CFS cases due to lack of recognition by health professionals.
Limitations
The study may not represent the entire UK population due to selection bias and the exclusion of non-consulting patients.
Participant Demographics
Participants were aged 18 to 64, with a majority being women and a diverse ethnic background in London.
Statistical Information
Confidence Interval
95%
Digital Object Identifier (DOI)
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