Repurposed for Aging
2024

Repurposing FDA-Approved Drugs for Aging

publication

Author Information

Author(s): Aleksic Sandra

Hypothesis

Can repurposed FDA-approved drugs extend healthspan and lifespan in aging populations?

Conclusion

Repurposing FDA-approved drugs may provide a cost-effective strategy to extend healthspan and lifespan by targeting aging biology.

Supporting Evidence

  • FDA-approved drugs can be repurposed to target aging biology.
  • Metformin has shown lifespan extension in preclinical models.
  • GLP1 receptor agonists and SGLT2 inhibitors have healthspan benefits beyond diabetes treatment.

Takeaway

Some medicines that are already approved for other uses might help people live healthier for longer as they age.

Methodology

The study discusses the potential of FDA-approved drugs as gerotherapeutics based on existing clinical evidence and preclinical models.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0449

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