Clinically relevant safety issues associated with St. John's wort product labels
2008

Safety Issues with St. John's Wort Labels

Sample size: 74 publication Evidence: low

Author Information

Author(s): Clauson Kevin A, Santamarina Marile L, Rutledge Jennifer C

Primary Institution: Nova Southeastern University, College of Pharmacy

Hypothesis

The study aims to evaluate the clinically relevant safety information included on labeling in a nationally representative sample of St. John's wort products from the USA.

Conclusion

The vast majority of SJW products fail to adequately address clinically relevant safety issues on their labeling.

Supporting Evidence

  • No product label provided information for all 8 evaluation criteria.
  • Three products provided information on 7 of the 8 criteria.
  • Four products provided no safety information whatsoever.
  • The average number of safety issues included on a product label was 1.91.

Takeaway

Most St. John's wort products don't tell you important safety information on their labels, which could lead to problems if you're taking other medications.

Methodology

The study evaluated the labeling of SJW products for eight clinically relevant safety issues using a nationally representative sample.

Limitations

The sample was limited to products available in the USA, and not all safety issues were assessed.

Digital Object Identifier (DOI)

10.1186/1472-6882-8-42

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication