Vitamin C and Opioid Use Reduction in Pain Management
Author Information
Author(s): Raoul Daoust, Jean Paquet, David Williamson, Vérilibe Huard, Caroline Arbour, Jeffrey J. Perry, Marcel Émond, Simon Berthelot, Patrick Archambault, Dominique Rouleau, Judy Morris, Alexis Cournoyer
Primary Institution: Hôpital du Sacré-Coeur de Montréal, Université de Montréal
Hypothesis
Does vitamin C reduce opioid consumption in patients with acute musculoskeletal pain?
Conclusion
The study suggests that vitamin C may help reduce opioid consumption in patients with acute musculoskeletal injuries.
Supporting Evidence
- Vitamin C has been shown to have analgesic properties.
- Previous studies indicated vitamin C can reduce opioid consumption post-surgery.
- Participants completed a diary to track pain and medication use.
Takeaway
This study looked at whether giving vitamin C can help people use less pain medicine after hurting themselves. It seems like it might help!
Methodology
A double-blind randomized controlled trial with two groups: one receiving vitamin C and the other a placebo, over a 14-day period.
Potential Biases
Potential bias due to high refusal and loss to follow-up rates.
Limitations
The study was not powered to detect differences in clinical outcomes, and the sample size was smaller than planned.
Participant Demographics
Mean age was 53 years, with 55% men.
Digital Object Identifier (DOI)
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