Hepatitis E virus is highly prevalent among pregnant women in Gabon, central Africa, with different patterns between rural and urban areas
2008

Hepatitis E Virus Prevalence in Pregnant Women in Gabon

Sample size: 840 publication Evidence: moderate

Author Information

Author(s): Caron Mélanie, Kazanji Mirdad

Primary Institution: Centre International de Recherches Médicales (CIRMF)

Hypothesis

What is the prevalence of anti-HEV IgG among pregnant women in Gabon?

Conclusion

The study found a high prevalence of Hepatitis E virus antibodies among pregnant women in Gabon, with significant differences between rural and urban areas.

Supporting Evidence

  • 14.1% of pregnant women tested positive for anti-HEV IgG.
  • The highest prevalence was found in Franceville, with 20.8%.
  • Urban areas had a significantly higher prevalence (13.5%) compared to rural areas (6.4%).
  • The study included 840 pregnant women from five cities.

Takeaway

Many pregnant women in Gabon have been exposed to Hepatitis E virus, especially in cities, which could be dangerous for their health.

Methodology

The study used serological tests to evaluate anti-HEV IgG prevalence in blood samples from pregnant women.

Potential Biases

Potential bias due to the socio-economic status of women attending free medical care centers.

Limitations

The study may not reflect the entire population due to the specific locations and socio-economic status of participants.

Participant Demographics

Pregnant women aged 14 to 44 years from five main cities in Gabon.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI reported for various prevalence rates.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1743-422X-5-158

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