Tuberculosis Outbreak Investigations in the United States, 2002–2008
2011

Tuberculosis Outbreak Investigations in the United States, 2002–2008

Sample size: 398 publication Evidence: moderate

Author Information

Author(s): Mitruka Kiren, Oeltmann John E., Ijaz Kashef, Haddad Maryam B.

Primary Institution: Centers for Disease Control and Prevention

Hypothesis

To understand circumstances of tuberculosis transmission that strain public health resources.

Conclusion

Substance abuse remains one of the greatest challenges to controlling tuberculosis transmission in the United States.

Supporting Evidence

  • Twenty-seven outbreaks, representing 398 patients, were reviewed.
  • Twenty-four of the 27 outbreaks involved primarily US-born patients.
  • Prolonged infectiousness due to provider- and patient-related factors was common.

Takeaway

This study looked at tuberculosis outbreaks in the U.S. from 2002 to 2008 and found that many of the people affected were born in the U.S. and had issues with substance abuse.

Methodology

A retrospective review of TB outbreak investigations in the U.S. for which CDC provided onsite assistance during 2002–2008.

Potential Biases

Social risk factors based on self-reported behavior may have been underdisclosed due to stigma.

Limitations

The review may lack generalizability to all TB outbreaks in the U.S. and may overrepresent outbreaks involving hard-to-reach populations.

Participant Demographics

Of the 398 patients, 364 (91%) were US-born, 265 (67%) were Black, and 259 (65%) were male.

Digital Object Identifier (DOI)

10.3201/eid1703.101550

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