Liver Enzymes and Inflammatory Markers in Severe COVID-19 Patients
Author Information
Author(s): Muacevic Alexander, Adler John R, Pavuluri Pratyusha, Menon M Girija, Tummalacharla Sarat Chandan, Sameer Raheem Shaik, Karpay Soujanya, Chepuri Phanindra
Primary Institution: RVM Institute of Medical Sciences and Research Center
Hypothesis
How does COVID-19 affect liver enzymes and inflammatory markers in hospitalized patients?
Conclusion
COVID-19 patients have elevated liver enzyme panels and inflammatory markers, indicating potential liver injury.
Supporting Evidence
- 179 out of 200 patients had elevated ALT levels.
- 191 out of 200 patients had elevated AST levels.
- 33 out of 200 patients had elevated ALP levels.
- 183 out of 200 patients showed elevated D-dimer levels.
- All patients had elevated IL-6 and CRP levels.
Takeaway
This study found that COVID-19 can hurt the liver, making liver tests important for sick patients.
Methodology
A retrospective case-control study comparing 200 hospitalized COVID-19 patients with 200 age- and sex-matched healthy controls.
Limitations
The study had a relatively small sample size and challenges in obtaining consent.
Participant Demographics
72% men and 28% women, aged 21-70 years.
Statistical Information
P-Value
≤0.0001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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