Metabolic Syndrome and Diabetes in Periodontitis Patients
Author Information
Author(s): Kosho Madeline X. F., Verhelst Alexander R. E., Teeuw Wijnand J., van Bruchem Sebastiaan, Nazmi Kamran, Gerdes Victor E. A., Loos Bruno G.
Primary Institution: Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam
Hypothesis
Patients with periodontitis may be more prone to having higher values of the clinical cardiometabolic parameters for metabolic syndrome due to shared risk factors.
Conclusion
The study found a high prevalence of metabolic syndrome and undiagnosed diabetes among periodontitis patients and controls in a dental school setting.
Supporting Evidence
- The prevalence of metabolic syndrome was found to be 68.2–81.8% in patients with generalized periodontitis.
- 20.5% of patients with generalized periodontitis had elevated HbA1c levels indicating undiagnosed diabetes.
- A significant number of patients were unaware of their suspected diabetes status.
- Oral health care professionals can contribute to early detection of diabetes.
Takeaway
This study shows that many people with gum disease might also have serious health issues like diabetes, and dentists can help find these problems early.
Methodology
The study recruited periodontitis patients and non-periodontitis controls from a dental school, assessed metabolic syndrome and diabetes prevalence using various definitions, and performed biochemical analyses.
Potential Biases
Potential bias due to the study population being drawn from a dental school, which may not represent the general population.
Limitations
The study lacked fasting glucose measurements, which are typically required to determine metabolic syndrome.
Participant Demographics
Participants were aged ≥ 40 years, with a mean age of 54.4 years; included both periodontitis patients and non-periodontitis controls.
Statistical Information
P-Value
0.094
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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