6-(4-Chlorophenyl)-2-isobutylimidazo[2,1-b][1,3,4]thiadiazole
2011
Study of a New Imidazo Compound
publication
Evidence: moderate
Author Information
Author(s): Fun Hoong-Kun, Hemamalini Madhukar, Prasad D. Jagadeesh, Nagaraja G. K., Anitha V. V.
Primary Institution: Universiti Sains Malaysia
Conclusion
The crystal structure of the compound shows weak π–π and C—H⋯π interactions without classical hydrogen bonds.
Supporting Evidence
- The imidazo[2,1-b][1,3,4]thiadiazole system is essentially planar.
- The dihedral angle between the imidazo and chlorophenyl rings is very small.
- There are no classical hydrogen bonds in the crystal structure.
Takeaway
Scientists created a new chemical compound and found that its structure is stable due to weak interactions between its parts.
Methodology
The compound was synthesized by refluxing 5-isobutyl-1,3,4-thiadiazole-2-amine with 4-chlorophenacyl bromide in ethanol.
Digital Object Identifier (DOI)
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